KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F5
All Species:
29.39
Human Site:
Y92
Identified Species:
46.19
UniProt:
Q15329
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15329
NP_001077057.1
346
37610
Y92
V
R
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Chimpanzee
Pan troglodytes
XP_511025
426
45548
Y78
V
R
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Rhesus Macaque
Macaca mulatta
XP_001094919
346
37697
Y92
V
R
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Dog
Lupus familis
XP_853833
304
33793
K65
E
G
I
D
L
I
E
K
K
S
K
N
S
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q61502
335
36766
Y82
V
R
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Rat
Rattus norvegicus
Q62814
300
33206
N65
L
I
E
K
K
S
K
N
S
I
Q
W
K
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517985
227
25092
Chicken
Gallus gallus
Q90977
403
43534
Y145
K
V
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Frog
Xenopus laevis
NP_001086706
375
40890
G65
T
N
V
L
E
G
I
G
L
I
E
K
K
S
K
Zebra Danio
Brachydanio rerio
NP_998597
393
42365
I66
V
L
E
G
I
G
L
I
E
K
K
S
K
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
Y295
H
V
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Honey Bee
Apis mellifera
XP_624285
300
34327
K65
G
I
G
L
I
E
K
K
S
K
N
S
I
Q
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799123
356
39484
V91
T
K
E
A
T
D
R
V
E
E
L
K
L
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130952
446
48668
Y171
E
V
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565831
483
52579
Y208
E
V
Q
K
R
R
I
Y
D
I
T
N
V
L
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
97.9
78.9
N.A.
88.1
82.6
N.A.
57.2
33
58.1
56.2
N.A.
20.6
41
N.A.
51.9
Protein Similarity:
100
62.2
98.5
82.6
N.A.
90.1
84.3
N.A.
60.6
49.6
68.8
66.1
N.A.
29.6
55.2
N.A.
65.1
P-Site Identity:
100
100
100
6.6
N.A.
100
13.3
N.A.
0
86.6
13.3
6.6
N.A.
86.6
0
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
100
33.3
N.A.
0
86.6
20
33.3
N.A.
86.6
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
31.3
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
45
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
86.6
N.A.
86.6
N.A.
N.A.
P-Site Similarity:
N.A.
86.6
N.A.
86.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
7
0
0
54
0
0
0
0
0
0
% D
% Glu:
20
0
20
0
7
7
7
0
14
7
7
0
0
7
54
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
7
7
0
14
0
7
0
0
0
0
0
7
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
14
7
0
14
7
60
7
0
67
0
0
7
7
0
% I
% Lys:
7
7
0
60
7
0
14
14
7
14
14
14
20
0
7
% K
% Leu:
7
7
0
14
7
0
7
0
7
0
7
0
7
54
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
7
0
0
7
60
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
54
0
0
0
0
0
0
0
7
0
0
7
7
% Q
% Arg:
0
27
0
0
54
54
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
7
0
0
14
7
0
14
7
7
7
% S
% Thr:
14
0
0
0
7
0
0
0
0
0
54
0
0
0
0
% T
% Val:
34
27
7
0
0
0
0
7
0
0
0
0
54
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _